Spinocerebellar Ataxia Type 6 (SCA6) Model-based In Vitro Assay I

Name: Spinocerebellar Ataxia Type 6 (SCA6) Model-based In Vitro Assay I
SKU: NRZP-0922-ZP1390
Rating: 5 (1 reviews)

[CAT#: NRZP-0922-ZP1390]

Species:: Human

Cell Types:: Neural Stem Cell

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Assay Overview

Description

Creative Biolabs offers custom in vitro functional assays based on neurological disease models. We have a variety of ready-to-use cell models which are validated for disease modeling, drug screening and toxicology testing. We also offer these assays as "cell line models" in a cryopreserved vial. Please feel free to contact us for more details.

Relevant Diseases

Spinocerebellar Ataxia Type 6 (SCA6)

Cell Models Information

Cell Models Used

iNeu™ Human Neural Stem Cells - Spinocerebellar Ataxia Type 6 (SCA6) Patient, Donor 63, Cat.#NRZP-0622-ZP90

Cell Models Overview

Spinocerebellar ataxia is a rare inherited autosomal dominant disorder that causes progressive cerebellar ataxia. There are different subtypes of the disease, which are based on mutations in the Ataxin gene family as well as in the calcium channel subunit genes. Creative Biolabs cell lines derived from spinocerebellar ataxia patients as well as familial and unaffected controls are excellent models for studying this rare genetic disorder. Creative Biolabs now offers custom human iPSC-derived brain cells or cardiomyocytes derived from patients with spinocerebellar ataxia.

Cell Models Control

iNeu™ Human Neural Stem Cells (Male), Source Fibroblasts (74 Yr Donor), Validated, Cat.#NCL-2101-ZP04
iNeu™ Human Neural Stem Cells (Female), Source Fibroblasts (64 Yr Donor), Cat.#NCL-2101-ZP05

Cell Types

Neural Stem Cell

Model Applications

• Studying pathogenesis at the cellular level
• Studying neural network formation and signal transmission in neural culture
• Neurotoxicity testing
• Preclinical drug efficacy testing
• Co-culture studies