iNeuMab™ Anti-APJ BBB Shuttle Antibody (NRZP-1222-ZP1221)

Name: iNeuMab™ Anti-APJ BBB Shuttle Antibody (NRZP-1222-ZP1221)
SKU: NRZP-1222-ZP1221
Rating: 5 (1 reviews)

[CAT#: NRZP-1222-ZP1221]

Host Species:: Mouse

Species Reactivity:: Human

Applications:: Agonist; In Vitro; In Vivo

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Product Overview

Description

Developing antibody agonists targeting the human apelin receptor (APJ) is a promising therapeutic approach for the treatment of chronic heart failure. The single-domain antibody (sdAb) agonist JN241-9 binds to the extracellular side of APJ, makes critical contacts with the second extracellular loop.

Species Reactivity

Human

Host Species

Mouse

Applications

Agonist; In Vitro; In Vivo

Relevant Diseases

Brain Injury

Target

AGTRL1

Official Name

AGTRL1

Full Name

G protein-coupled receptor APJ

Alternative Names

APJ; APJ (apelin) receptor; APJ receptor; APJR; G protein-coupled receptor APJ; G-protein coupled receptor APJ; G-protein coupled receptor HG11; HG11; HG11 orphan receptor; angiotensin II receptor-like 1; angiotensin receptor-like 1; apelin receptor

Publications