iNeuMab™ Anti-MMP9 metalloproteinase BBB Shuttle Antibody (NRZP-0423-ZP273)
[CAT#: NRZP-0423-ZP273]
- Species Reactivity:
- Human; Mouse; Rat
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-MMP-9 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-708 (full-length) of rat MMP9 also known as matrix metalloproteinase 9, 92 kDa type IV collagenase, 92 kDa gelatinase, gelatinase B and GELB, accession number NP_112317)
Human: 68% identity (482/708 amino acids identical)
Mouse: 74% identity (548/731 amino acids identical)
<50% identity with MMP2
Human: 68% identity (482/708 amino acids identical)
Mouse: 74% identity (548/731 amino acids identical)
<50% identity with MMP2
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Isotype
IgG2a
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
MMP-9
Official Name
MMP9
Full Name
MMP9
Alternative Names
MMP9; CLG4B; GELB; MANDP2; MMP-9; 92 kDa type IV collagenase; 92 kDa gelatinase; gelatinase B; matrix metallopeptidase 9
Uniprot ID
NP_112317
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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