iNeuMab™ Anti-NGL-1 (Netrin-G1 ligand) BBB Shuttle Antibody (NRZP-0423-ZP299)
[CAT#: NRZP-0423-ZP299]
- Species Reactivity:
- Human; Mouse; Rat
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-LRRC4C BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 551-640 (cytoplasmic C-terminus) of human NGL-1 (also known as Netrin-G1 ligand, Leucine-rich repeat-containing 4C, LRRC4C, KIAA1580 and UNQ292/PRO331, accession number Q9HCJ2)
Mouse: 100% identity (90/90 amino acids identical)
Rat: 100% identity (90/90 amino acids identical)
<40% identity with NGL-2 and NGL-3
Mouse: 100% identity (90/90 amino acids identical)
Rat: 100% identity (90/90 amino acids identical)
<40% identity with NGL-2 and NGL-3
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Isotype
IgG1
Research Areas
CAMs
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
LRRC4C
Official Name
LRRC4C
Full Name
NGL-1/LRRC4C
Alternative Names
NGL-1; NGL1
Uniprot ID
Q9HCJ2
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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