iNeuMab™ Anti-TRIP8b (exon 1b) BBB Shuttle Antibody (NRZP-0423-ZP437)
[CAT#: NRZP-0423-ZP437]
- Species Reactivity:
- Rat; Mouse; Human
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-PEX5L BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-205 (exon 1b as MSDSEMDGRTHIPSLLNALLSRNRVMQMSYL, exon 2 and constant region) of mouse TRIP8b (also known as TPR-containing Rab8b-interacting protein, Peroxisome biogenesis factor 5-like, Peroxin-5- or PEX5-related/like protein, Pex5Rp, Pex5l, Pex5r, Pex2 and Pxr2, accession number Q8C437-3)
Rat:>90% identity (150/163 amino acids identical), 100% identity with 1b-specific sequence
Human:>90% identity (163/174 amino acids identical), 100% identity with 1b-specific sequence
Rat:>90% identity (150/163 amino acids identical), 100% identity with 1b-specific sequence
Human:>90% identity (163/174 amino acids identical), 100% identity with 1b-specific sequence
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG1
Research Areas
Ion channels
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
PEX5L
Official Name
PEX5L
Full Name
TRIP8b (exon 1b)
Alternative Names
PEX5R; PXR2; TRIP8b
Uniprot ID
Q8C437-3
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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