NeuroMab™ Anti-Amyloid Beta BBB Shuttle Antibody(NRZP-1022-ZP4063)
[CAT#: NRZP-1022-ZP4063]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- In Vitro
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Lot Number
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Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Applications
In Vitro
Relevant Diseases
Alzheimer's Disease
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
AmyloidBeta
Official Name
Amyloid Beta
Full Name
Amyloid Beta
Alternative Names
APP; Aβ; Abeta; Amyloid β
Product Pictures
IHC
Figure 1 Immunostaining of mouse APP/PS1 sections with ni3A and pa2H.
FuncS
Figure 2 In vivo imaging of Aβ after direct application to the brain.
FuncS
Figure 3 Blood clearance of VHH-pa2H-DTPA-111 In in APP swe /PS1dE9 transgenic mice (APP/PS1) and wild-type (WT) littermates.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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