Rat Anti-Human LHX6 Monoclonal Antibody (CBP2374)

Product Overview

Description

LHX6 is a transcription factor that belongs to the LIM-homeobox protein family. LHX6 contains two LIM domains, followed by one homeodomain (HD). The protein has been shown to play an important role during neurodevelopment where it functions as a cell fate regulator that controls differentiation and development of neural cells, especially cholinergic and GABAergic neurons1. In the nervous system, LHX6 is mainly expressed in neurons, including motor neurons, interneurons, and sensory neurons.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Rat

Isotype

IgG1, κ

Clone Number

CBP2374

Applications

IHC-P

Application Notes

IHC-P (5.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

LHX6

Official Name

LHX6

Full Name

LIM/homeobox protein Lhx6

Alternative Names

LIM/homeobox protein Lhx6

Gene ID

26468 (Human); 16874 (Mouse)

Uniprot ID

Q9UPM6 (Human); Q9R1R0 (Mouse)

References

1. Zhou C, et al. 2015 FASEB J. 29(10):4083
2. Nathalia E, et al. 2018. Rom J Intern Med. 56(3):135
3. Wullimann MF, et al. 2009. Integr Zool. 4(1):123

Publications