Mouse Anti-Human TICAM-2 Monoclonal Antibody (CBP3699)
[CAT#: NAB201238LS]
Anti-TICAM-2 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
TICAM-2, also known as TRIF-related adaptor molecule (TRAM), is a TIR domain containing protein that was found to act as an adaptor molecule during LPS-induced innate immune response. TICAM-2 is essential for bridging the interaction between TLR4 and TICAM-1. TICAM-2 is also involved in the regulation of the IL-18 signaling pathway, acting as a sorting adaptor that recruits MYD88 from the cytosol to the membrane region upon activation of IL-1/IL-18 receptors.
Immunogen
Full length human TICAM-2 recombinant protein expressed in E. coli.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a, κ
Clone Number
CBP3699
Applications
WB
Application Notes
WB (0.5-2.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
TICAM-2
Official Name
TICAM2
Full Name
Toll like receptor adaptor molecule 2
Alternative Names
TICAM2; MyD88-4; TICAM-2; TIRAP3; TIRP; TRAM; toll like receptor adaptor molecule 2
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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