Mouse Anti-Human Tollip Monoclonal Antibody (CBP3985)
[CAT#: NAB2012936LS]
Anti-Tollip Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Tollip, also known as Toll interacting protein, is a ubiquitin-binding protein and an inhibitory adaptor protein involved in IL-1 and Toll-like receptor (TLR) signaling pathway. Alterations in Tollip gene expression levels has been linked to tuberculosis and idiopathic pulmonary fibrosis, suggesting a role for Tollip in innate immune system. Tollip has also been reported to mediate autophagic clearance of poly-ubiquitinated proteins.
Immunogen
Full length human recombinant Tollip (NP_061882) produced in HEK293T cell
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP3985
Applications
WB
Application Notes
WB (1.0-5.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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