iNeuMab™ Anti-CXCL13 BBB Shuttle Antibody (NRZP-1022-ZP3436)

Name: iNeuMab™ Anti-CXCL13 BBB Shuttle Antibody (NRZP-1022-ZP3436)
SKU: NRZP-1022-ZP3436
Rating: 5 (1 reviews)

[CAT#: NRZP-1022-ZP3436]

Host Species:: Humanized

Species Reactivity:: Human; Mouse; Cynomolgus Monkey

Applications:: WB; ELISA; IHC; Inhib; Neut; In Vitro; In Vivo

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human; Mouse; Cynomolgus Monkey

Clonality

Monoclonal

Host Species

Humanized

Isotype

IgG

Applications

WB; ELISA; IHC; Inhib; Neut; In Vitro; In Vivo

Relevant Diseases

Multiple Sclerosis; Neuroinflammation

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

CXCL13

Official Name

CXCL13

Full Name

chemokine (C-X-C motif) ligand 13

Alternative Names

BCA-1; Angie; C-X-C motif chemokine 13; CXC chemokine BLC; ANGIE2; B lymphocyte chemoattractant; B cell-attracting chemokine 1; BLR1L; Small-inducible cytokine B13; SCYB13; ANGIE; BLC; BCA1

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