iNeuMab™ Anti-Kv1.1 potassium channel (external) BBB Shuttle Antibody (NRZP-0423-ZP202)
[CAT#: NRZP-0423-ZP202]
- Species Reactivity:
- Rat; Mouse
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-Kv1.1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Synthetic peptide amino acids 191-208 (ELKDDKDFTGTIHRIDNTC, extracellular domain) of rat Kv1.1 (also known as potassium voltage-gated channel subfamily A member 1, IA, RBKI, RCK1, accession number P10499)
Mouse: 100% identity (18/18 amino acids identical)
Human: 94% identity (17/18 amino acids identical)
Mouse: 100% identity (18/18 amino acids identical)
Human: 94% identity (17/18 amino acids identical)
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse
Clonality
Monoclonal
Isotype
IgG2b
Research Areas
K+ channels
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
Kv1.1
Official Name
KCNA1
Full Name
Kv1.1 K+ channel (external)
Alternative Names
KCNA1; AEMK; EA1; HBK1; HUK1; KV1.1; MBK1; MK1; RBK1; potassium voltage-gated channel subfamily A member 1
Uniprot ID
P10499
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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