iNeuMab™ Anti-Thyroid hormone receptor beta1 BBB Shuttle Antibody (NRZP-0423-ZP428)
[CAT#: NRZP-0423-ZP428]
- Species Reactivity:
- Rat; Mouse; Human
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-THRB BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-461 (full-length) of human Thyroid hormone receptor beta1 (also known as Nuclear receptor subfamily 1 group A member 2, c-erbA-2, c-erbA-beta, THRB, ERBA2, NR1A2 and THR1, accession number P10828)
Mouse: 96% identity (445/461 amino acids identical)
Rat: 95% identity (442/461 amino acids identical)
>75% identity with Thyroid hormone receptor beta2>80% identity with Thyroid hormone receptor alpha1
Mouse: 96% identity (445/461 amino acids identical)
Rat: 95% identity (442/461 amino acids identical)
>75% identity with Thyroid hormone receptor beta2>80% identity with Thyroid hormone receptor alpha1
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG2b
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
THRB
Official Name
THRB
Full Name
Thyroid hormone receptor beta1
Alternative Names
THRB; C-ERBA-2; C-ERBA-BETA; ERBA2; GRTH; NR1A2; PRTH; THR1; THRB1; THRB2; thyroid hormone receptor beta
Uniprot ID
P10828
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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