NeuroMab™ Anti-Aβ BBB Shuttle Antibody(NRZP-1222-ZP1037)

[CAT#: NRZP-1222-ZP1037]

Host Species:: Mouse

Species Reactivity:: Human

Applications:: In Vitro

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Description

The Aβ peptide exists in several forms, including full-length Aβ1-42 and Aβ1-40 - and the N-truncated species, pyroglutamate Aβ3-42 and Aβ4-42, which appear to play a major role in neurodegeneration. The murine antibody binds specifically to soluble, non-plaque N-truncated Aβ species, which offers new routes for active and passive immunisation against AD.