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NeuroMab™ Anti-FGF13 (Fibroblast growth factor 13) BBB Shuttle Antibody, Clone N91/27
[CAT#: NRZP-0423-ZP101]
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC; IP; ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-FGF13 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 53-245 of human FGF13a (also known as fibroblast growth factor homologous factor 2a or FHF2a, accession number Q92913)
Mouse: 99% identity (192/193 amino acids identical)
Rat: 97% identity (183/188 amino acids identical)
97% identity with FGF13b (184/188 amino acids identical)
>60% identity with FGF11, FGF12 and FGF14
Mouse: 99% identity (192/193 amino acids identical)
Rat: 97% identity (183/188 amino acids identical)
97% identity with FGF13b (184/188 amino acids identical)
>60% identity with FGF11, FGF12 and FGF14
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
N91/27
Applications
WB; IHC; IP; ICC
Application Notes
Cross-reacts with FGF13a and FGF13b;Does not cross-react with FGF11, FGF12 or FGF14 expressed in heterologous cells
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
FGF13
Official Name
FGF13
Full Name
FGF13/FHF2
Alternative Names
FGF 13; FGF 2; FGF-13; FGF13; FGF13; FGF2; FHF 2; FHF-2; FHF2; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; OTTHUMP00000024143; THUMP00000024144
Uniprot ID
Q92913
Product Pictures
IB
Fig. 1 Transfected cell immunoblot: extracts of whole rat brain homogenate (WBH) and COS cells transfected with GFP-tagged FGF11/FHF3 and FGF13/FHF2 and untagged Kv2.1 plasmids and probed with N91/27 (left) and N52A/42 (right) TC supe.
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
