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Creative Biolabs
Product

NeuroMab™ Anti-FGF13B/FHF2B BBB Shuttle Antibody, Clone N225A/10

[CAT#: NRZP-0423-ZP102]

Species Reactivity:
Human; Rat; Mouse
Applications:
WB; IHC; ICC

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Product Overview

Description

The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-FGF13 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.

Immunogen

Synthetic peptide amino acids 1-20 (MALLRKSYSEPQLKGIVTKL) of human FHF2B (also known as Fibroblast growth factor homologous factor 2B, Fibroblast growth factor 13B and FGF13B, accession number Q92913-2)
Rat: 100% identity (20/20 amino acids identical)
Mouse: 100% identity (20/20 amino acids identical)
55% identity with FGF13A/FHF2A

Construction

We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.

Species Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

N225A/10

Applications

WB; IHC; ICC

Application Notes

Does not cross-react with FGF13A/FHF2A

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

FGF13

Official Name

FGF13

Full Name

FGF13/FHF2, B isoform

Alternative Names

FGF 13; FGF 2; FGF-13; FGF13; FGF13; FGF2; FHF 2; FHF-2; FHF2; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; OTTHUMP00000024143; THUMP00000024144

Uniprot ID

Q92913-2
Product Pictures
IB

Fig. 1 Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged FGF13B/FHF2B, FGF13A/FHF2A or untagged Kv2.1 plasmid and probed with N225A/10 (left) or N86/8 (right) TC supe.

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For Research Use Only. Not For Clinical Use.
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