NeuroMab™ Anti-IL-6 BBB Shuttle Antibody,Clone NR2473P
- Host Species:
- Chimeric
- Species Reactivity:
- Human
- Applications:
- WB; Inhib; Neut; In Vitro; In Vivo
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1 shows a graph showing the binding of cCLB8 to human recombinant IL-6.
Figure 2 graph showing the inhibition of IL-6-mediated IgM mu secretion from SKW6.4 cells by cCLB8.
Figure 3 is a graph showing the inhibition of IL-6-mediated MCP-1 production by cCLB8.
Figure 4. Western blot images showing cCLB8 inhibits IL-6 signaling in THP-1 human monocytic leukemia cells.
Figure 5 is a graph showing that cCLB8 inhibits IL-6-induced serum amyloid A production in HepG2 cells.
Figure 6 is a graph showing the ability of cCLB8 to neutralize rhIL-6-induced cell proliferation.
Figure 7 is a graph showing the relative reduction in body weight loss in tumor-bearing mouse hosts treated with anti-human and anti-mouse IL-6 antibodies.
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