Mouse Anti-IL-6 Monoclonal Antibody (CBP2538)

Product Overview

Description

Mouse anti-human interleukin-6 antibody, recognizes human interleukin-6 (IL-6), a cytokine, which is an effective inducer of acute immune response.

Immunogen

Recombinant full-length human IL-6 expressed in E. coli.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2538

Applications

ELISA; IHC-Fr

Application Notes

FuncS: 20pg neutralizes activity of 1U of IL-6

Relevant Diseases

Amyotrophic Lateral Sclerosis; Frontotemporal Dementia

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.09% Sodium Azide

Preservatives

YES

Concentration

1 mg/ml

Purification

Affinity chromatography

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

IL-6

Official Name

IL6

Full Name

Interleukin 6 (IL-6)

Alternative Names

IL6; BSF2; HGF; HSF; IFNB2; IL-6; BSF-2; CDF; IFN-beta-2; interleukin 6

Gene ID

3569(Human)

Uniprot ID

P05231(Human)

References

1. Wijdenes, J. et al. (1991) Human recombinant dimeric IL-6 binds to its receptor as detected by anti IL-6 monoclonal antibodies.
2.Dechaud, H. et al. (1998) Evaluation of endometrial inflammation by quantification of macrophages, T lymphocytes and interleukin-1 and -6 in human endometrium.
3. Kimoff, R.J. et al. (2011) Increased upper airway cytokines and oxidative stress in severe obstructive sleep apnoea.

Publications