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Creative Biolabs
Product

Mouse Anti-RAB27A Monoclonal Antibody (CBP2685)

[CAT#: NAB20101761CR]

Mouse Monoclonal (1C4B8) to RAB27A

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IHC; WB; ELISA

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Product Overview

Description

Rab27a is a member of a large family of Ras-related small GTPases. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Recent studies suggest that Rab27a is associated with melanosomes in pigmented cells and regulates melanosome transport via its interaction with actin-based cellular motors such as myosin Va and myosin VIIa. RAB27A is also required for regulated secretion in cytotoxic T lymphocytes. Rab27a is implicated in several diseases, including Griscelli syndrome, choroideremia, and the Hermansky-Pudlak syndrome mouse model, gunmetal.

Expression Host

Mammalian cells

Immunogen

RAB27A fusion protein Ag12382

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2685

Applications

IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Growth and Development

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

407 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

RAB27A

Official Name

RAB27A

Full Name

RAB27A, member RAS oncogene family

Alternative Names

GS2; GTP binding protein Ram; HsT18676; Rab 27; RAB27; RAB27A; RAM; Ras related protein Rab 27A

Gene ID

5873(Human)

Uniprot ID

P51159(Human)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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