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Creative Biolabs
Product

Mouse Anti-Human DNMT3B Monoclonal Antibody (CBP3757)

[CAT#: NAB2012146LS]

Anti-DNMT3B Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB

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Product Overview

Description

DNA (Cytisube-5-)-Methyltransferase 1 (DNMT-1), is an enzyme that has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. This enzyme associates with DNA replication sites in the S phase and methylates CpG residues to maintain the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance.

Immunogen

Partial human DNMT3B recombinant protein (1-355 a.a.) expressed in E. coli.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3757

Applications

WB

Application Notes

WB (0.1-1.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

DNMT3B

Official Name

DNMT3B

Full Name

DNA (cytosine-5-)-methyltransferase 3 beta

Alternative Names

DNMT3B; ICF; ICF1; M.HsaIIIB; DNA (cytosine-5-)-methyltransferase 3 beta; DNA methyltransferase 3 beta
Publications

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For Research Use Only. Not For Clinical Use.
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