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Creative Biolabs
Product

Anti-MAGUK (CBP3888)

[CAT#: NAB2012450LS]

Anti-MAGUK (pan reactive) Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Rat; Drosophila
Applications:
WB; IHC-P

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Product Overview

Description

Membrane-associated guanylate kinases (MAGUK) are a superfamily of scaffolding proteins defined by the presence of a guanylate kinase (GUK) domain. MAGUKs, such as PSD-95, SAP97, PSD-83, CASK, and MAGIs are involved in the synaptic development and function where they are important for the spatial organization of both pre- and postsynaptic proteins, including glutamate and other receptors.

Immunogen

This monoclonal antibody was raised against a fusion protein corresponding to amino acids 77-299 of human PSD-95.

Species Reactivity

Human; Rat; Drosophila

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3888

Applications

WB; IHC-P

Application Notes

WB (0.5-10.0 µg/ml); IHC-P (0.5-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

MAGUK

Official Name

MAGUK

Full Name

Membrane-associated guanylate kinases

Alternative Names

Membrane-associated guanylate kinase; MAGUK
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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