iNeuMab™ Anti-ADAM22-extracellular BBB Shuttle Antibody (NRZP-0423-ZP6)
[CAT#: NRZP-0423-ZP6]
- Species Reactivity:
- Mouse; Rat
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-ADAM22 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 444-526 (extracellular disintegrin domain) of mouse ADAM22 (also known as Disintegrin and metalloproteinase domain-containing protein 22, Metalloproteinasedisintegrin ADAM22-3, Metalloproteinase-like disintegrin-like and cysteine-rich protein 2 and MDC2, accession number Q9R1V6)
Human: 95% identity (79/83 amino acids identical)
Rat: 100% identity (83/83 amino acids identical)
>50% identity with ADAM11 and ADAM23
Human: 95% identity (79/83 amino acids identical)
Rat: 100% identity (83/83 amino acids identical)
>50% identity with ADAM11 and ADAM23
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Mouse; Rat
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
ADAM22
Official Name
ADAM22
Full Name
ADAM22 (extracellular)
Alternative Names
ADAM22; ADAM 22; MDC2; ADAM metallopeptidase domain 22; EIEE61
Uniprot ID
Q9R1V6
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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