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Creative Biolabs

Mouse Anti-Rat ADAM22 Monoclonal Antibody (CBP3747)

[CAT#: NAB2012127LS]

Anti-ADAM22 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Rat
Applications:
WB

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Product Overview

Description

ADAM22 is a member of the ADAM (integrin and metalloproteinase domain) family and is involved in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity because it does not have a zinc-binding motif. This protein is highly expressed in the brain and may act as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system.

Immunogen

A fusion protein corresponding to amino acids 757-857 (cytoplasmic region) of mouse ADAM22 protein.

Species Reactivity

Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG

Clone Number

CBP3747

Applications

WB

Application Notes

WB (1.0-10.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

ADAM22

Official Name

ADAM22

Full Name

Disintegrin and metalloproteinase domain-containing protein 22

Alternative Names

ADAM22; ADAM 22; MDC2; ADAM metallopeptidase domain 22; EIEE61

Gene ID

53616 (Human); 11496 (Mouse)

Uniprot ID

Q9P0K1 (Human); Q9R1V6 (Mouse)
Publications

Publications (0)

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