iNeuMab™ Anti-APRIL BBB Shuttle Antibody (NRZP-1022-ZP2699)

Name: iNeuMab™ Anti-APRIL BBB Shuttle Antibody (NRZP-1022-ZP2699)
SKU: NRZP-1022-ZP2699
Rating: 5 (1 reviews)

[CAT#: NRZP-1022-ZP2699]

Host Species:: Human

Species Reactivity:: Human

Applications:: ELISA; Neut; In Vitro; Inhib; Antagonist

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Human

Applications

ELISA; Neut; In Vitro; Inhib; Antagonist

Relevant Diseases

Multiple Sclerosis; Neuroinflammation

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

APRIL

Official Name

TNFSF13

Full Name

tumor necrosis factor (ligand) superfamily, member 13

Alternative Names

TALL2; ZTNF2; TRDL-1; TNF- and APOL-related leukocyte expressed ligand 2; CD256; APRIL; A proliferation-inducing ligand; TNF-related death ligand 1; UNQ383/PRO715; CD antigen CD256; Tumor necrosis factor ligand superfamily member 13; TALL-2

Publications