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NeuroMab™ Anti-PlexinA1 BBB Shuttle Antibody,Clone NR1406P
- Host Species:
- Chimeric
- Species Reactivity:
- Human; Mouse
- Applications:
- ELISA; In Vitro; Agonist
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Research Use Only
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Fig.1 illustrates a plot showing binding responses measured by immobilizing mouse chimeric antibodies hPANL#240-mFc, 359B-2-2-3-6-mFc, PXB693-mFc, PXB727-mFc, and PXB361b-mFc onto Protein G biosensors, and applying human PlexinA1 and mouse PlexinA1 thereto.
Sema3A(+) represents values measured with the addition of 0.8 μg/mL of mouse semaphorin 3A, and Sema3A(−) represents values measured without the addition of mouse semaphorin 3A.
![](https://img.creative-biolabs.com/neuros/productImages/NRZP-1022-ZP2513-1.png)
Fig.2 illustrates plots showing dose-dependent semaphorin 3A-like agonistic activities of anti-PlexinA1 antibodies for mouse bone marrow-derived dendritic cell contraction.
Sema3A(+) represents values measured with the addition of 0.8 μg/mL of mouse semaphorin 3A, and Sema3A(−) represents values measured without the addition of mouse semaphorin 3A.
![](https://img.creative-biolabs.com/neuros/productImages/NRZP-1022-ZP2513-2.png)
Fig.3 illustrates plots showing semaphorin 3A-like agonistic activities of anti-PlexinA1 antibodies against U87-MG cells.
Sema3A(+) represents values measured with the addition of 1.6 μg/mL of human semaphorin 3A.
![](https://img.creative-biolabs.com/neuros/productImages/NRZP-1022-ZP2513-3.png)
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