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Creative Biolabs

Anti-ALDH2 Monoclonal Antibody (CBP3687)

[CAT#: NAB201223LS]

Anti-ALDH2 Monoclonal Antibody [HRP]

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
WB; IHC-P

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Product Overview

Description

ALDH2 is a member of the aldehyde dehydrogenase family. In the human brain, ALDH2 is the main aldehyde metabolizing enzyme, which is essential for the metabolism and detoxification of endogenous and exogenous aldehyde substrates. Correspondingly, recent studies report that the level of ALDH2 in the brains of patients with Parkinson's and Alzheimer's disease is dysregulated, indicating that toxic aldehydes are the cause of neurodegenerative diseases and potential therapeutic targets.

Immunogen

Purified recombinant human ALDH2 fragments expressed in E. coli.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3687

Applications

WB; IHC-P

Application Notes

WB (0.5-2.0 µg/mL); IHC-P (10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties

Form

Liquid

Formulation

50% glycerol in aqueous buffered solutions with preservatives.

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon receipt, the antibody solution should be stored undiluted at-20°C, and protected from prolonged exposure to light.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

ALDH2

Official Name

ALDH2

Full Name

Aldehyde dehydrogenase 2

Alternative Names

ALDH2; ALDH-E2; ALDHI; ALDM; aldehyde dehydrogenase 2 family (mitochondrial); aldehyde dehydrogenase 2 family member

Gene ID

217 (Human); 11669 (Mouse)

Uniprot ID

P05091 (Human); P47738 (Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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