Mouse Anti-Human Laforin Monoclonal Antibody (CBP3748)

[CAT#: NAB2012128LS]

Anti-Laforin Monoclonal Antibody

Host Species:: Mouse

Species Reactivity:: Human

Applications:: WB; IHC-P

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Product Overview

Description

Laforin, encoded by the gene EPM2A, is a dual-specificity phosphatase protein.

Immunogen

Fusion protein corresponding to amino acids 1-331 (full-length) of human Laforin

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG

Clone Number

CBP3748

Applications

WB; IHC-P

Application Notes

WB (1.0-5.0 µg/mL); IHC-P (2.5-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Laforin

Official Name

EPM2A

Full Name

Laforin

Alternative Names

EPM2A; Laforin

References

1. Gentry MS, et al. 2013. FEBS J. 280(2):525-37.
2. Sankhala RS, et al. 2015. J Biol chem. 290(8):4552-9.
3. Singh PK, et al. 2012. Mol Cell Biol. 32(3):652-63.
4. Mittal S, et al. 2007. Hum Mol Genet. 16(7):753-62.
5. Tagliabracci VS, et al. 2007. Proc. Natl. Acad. Sci U S A. 104(49):19262-6

Publications