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Creative Biolabs

Rat Anti-Mouse CD182 Monoclonal Antibody (CBP3961)

[CAT#: NAB2012892LS]

Anti-CD182 Monoclonal Antibody

Host Species:
Rat
Species Reactivity:
Mouse
Applications:
FC

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Product Overview

Description

CD182, also known as CXCR2, is a G-protein coupled receptor with 7 transmembrane regions that is involved in chemotaxis, neutrophil activation and angiogenesis. CXCR2 is expressed by neutrophils, basophils, subset of T cells, monocytes, macrophages, NK and NKT cells. Its ligands are CXCL1, CXCL2, CXCL3 and CXCL5.

Immunogen

Mouse CXCR2-transfected cells.

Species Reactivity

Mouse

Clonality

Monoclonal

Host Species

Rat

Isotype

IgG2a, κ

Clone Number

CBP3961

Applications

FC

Application Notes

FCM (≤1.0 µg per million cells in 100 µL volume)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD182

Official Name

CXCR2

Full Name

C-X-C motif chemokine receptor 2

Alternative Names

CD163

Gene ID

3579 (Human); 12765 (Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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