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Creative Biolabs

Mouse Anti-MKI67 Monoclonal Antibody (CBP6767)

[CAT#: NAB2007FY1716]

Progenitors

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IHC; IF

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Product Overview

Description

The antigen KI-67, also known as Ki-67 or MKI67, is a protein encoded by the MKI67 gene in humans (an antigen recognized by the monoclonal antibody Ki-67). Antigen KI-67 is a nuclear protein associated with cell proliferation. Changing the expression level of Ki-67 does not significantly affect cell proliferation in vivo. Ki-67 mutant mice develop normally, and cells lacking Ki-67 proliferate effectively. In addition, it is related to ribosomal RNA transcription. Inactivation of KI-67 antigen leads to inhibition of ribosomal RNA synthesis.

Epitope

Binds to an located within the peptide sequence PLSLSTCLFGRGIEC

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6767

Applications

IHC; IF

Application Notes

IHC: 1:200-1:500
IF: 2-10 µg/ml
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, 40% glycerol

Preservatives

0.02% Sodium azide

Concentration

1 mg/ml

Purification

Protein A purified

Shipping

Gel Pack

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

Ki67

Official Name

MKI67

Full Name

Antigen KI-67

Alternative Names

MKI67; marker of proliferation Ki-67; KIA; MIB-; MIB-1; PPP1R105

Gene ID

4288(Human); 17345(Mouse); 246042(Rat)

Uniprot ID

P46013(Human); E9PVX6(Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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