iNeuMab™ Anti-IRSp53/BAIAP2 BBB Shuttle Antibody (NRZP-0423-ZP179)
[CAT#: NRZP-0423-ZP179]
- Species Reactivity:
- Human; Mouse; Rat
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-BAIAP2 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-250 (N-terminus) of human BAIAP2 (also known as Brain-specific angiogenesis inhibitor 1-associated protein 2, BAI-associated protein 2, BAI1-associated protein 2, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa, Insulin receptor tyrosine kinase 53 kDa substrate, Insulin receptor tyrosine kinase substrate protein p53, Fas ligand-associated factor 3, BAP2, IRS-58, IRSp53/58, IRSp53 and FLAF3, accession number Q9UQB8)
Mouse: 97% identity (243/250 amino acids identical)
Rat: 97% identity (242/250 amino acids identical)
<50% identity with BAIAP2L1
Mouse: 97% identity (243/250 amino acids identical)
Rat: 97% identity (242/250 amino acids identical)
<50% identity with BAIAP2L1
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Isotype
IgG1
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
BAIAP2
Official Name
BAIAP2
Full Name
IRSp53/BAIAP2
Alternative Names
BAIAP2; BAP2; FLAF3; IRSP53; BAI1 associated protein 2; BAR/IMD domain containing adaptor protein 2; WAML
Uniprot ID
Q9UQB8
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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