iNeuMab™ Anti-Stonin-2 BBB Shuttle Antibody (NRZP-0423-ZP398)
[CAT#: NRZP-0423-ZP398]
- Species Reactivity:
- Rat; Mouse; Human
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-STON2 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-555 (N-terminus) of human Stonin-2 (also known as Stoned B, STON2, STN2 and STNB, accession number Q8WXE9)
Mouse: 86% identity (480/556 amino acids identical)
Rat: 85% identity (474/555 amino acids identical)
>50% identity with Stonin-1 (73/135 amino acids) near Cterminus
Mouse: 86% identity (480/556 amino acids identical)
Rat: 85% identity (474/555 amino acids identical)
>50% identity with Stonin-1 (73/135 amino acids) near Cterminus
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG2b
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
STON2
Official Name
STON2
Full Name
Stonin-2
Alternative Names
Stonin 2
Uniprot ID
Q8WXE9
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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