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Creative Biolabs
Product

Anti-LRP4 (CBP3825)

[CAT#: NAB2012325LS]

Anti-LRP4 (NH2 terminus) Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
WB; IHC-P

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Product Overview

Description

Low-density lipoprotein receptor-related protein 4 (LRP4), also known as LRLR dan and multiple epidermal growth factor-like domains 7 (MEGF7), is a member of the LDLR family and has a large N terminus. LRP4 may help regulate Wnt signaling and is a receptor for agrin to activate muscle-specific kinase (MuSK), a critical tyrosine kinase in neuromuscular junction formation.

Immunogen

This monoclonal antibody was raised against a fusion protein corresponding to amino acids 26-350 (extracellular N-terminus) of mouse LRP4 protein.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Clone Number

CBP3825

Applications

WB; IHC-P

Application Notes

WB (1.0-10.0 µg/mL); IHC-P (10.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

LRP4

Official Name

LRP4

Full Name

Low-density lipoprotein receptor-related protein 4

Alternative Names

LRP4; CLSS; LRP-4; LRP10; MEGF7; SOST2; CMS17; Low density lipoprotein receptor-related protein 4; LDL receptor related protein 4

Gene ID

4038 (Human); 228357 (Mouse)

Uniprot ID

O75096 (Human); Q8VI56 (Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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