RH421
[CAT#: NRZP-0922-ZP5150]
Fast-Responding Membrane Potential Dyes
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Product Overview
Description
Fast-response membrane voltage-sensitive dyes are styryl dyes whose fluorescence intensity changes with changes in membrane potential. The dyes also undergo spectral shifts with changes in membrane potential, allowing ratiometric measurements. Fast-response dyes have been used to measure electrical activity in nerve and heart cells.
RH237, RH414, RH421, and RH795 are fast-response potential probes commonly used for functional imaging of neurons. RH421 exhibits>20% fluorescence change per 100 mV on neuroblastoma cells. The physiological effects of these dyes may differ, for example RH414 causes arterial constriction during cortical staining, whereas the spectrally similar dye RH795 does not.
RH237, RH414, RH421, and RH795 are fast-response potential probes commonly used for functional imaging of neurons. RH421 exhibits>20% fluorescence change per 100 mV on neuroblastoma cells. The physiological effects of these dyes may differ, for example RH414 causes arterial constriction during cortical staining, whereas the spectrally similar dye RH795 does not.
Properites
Detection Method
515/704 nm
Detection Range
515/704 nm
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Publications (0)
For Research Use Only. Not For Clinical Use.
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