Product
Anti-Doublecortin Monoclonal Antibody (CBP2383)
[CAT#: NAB2010403LS]
Anti-Doublecortin Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Mouse
- Applications:
- WB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Doublecortin (DCX) is a microtubule-associated protein that is predominantly expressed in embryonic brains by neuronal precursor cells or immature neurons. DCX is also expressed in the adult brains in regions such as subventricular zones and dentate gyrus, where neuronal precursor cells are localized, and thus has been widely used as a marker for neurogenesis. Doublecortin binds to the microtubule cytoskeleton and stabilizes microtubule bundles. Mutation in DCX has been identified in diseases such as X-linked lissencephaly and double cortex syndrome.
Immunogen
Full-length human recombinant DCX protein produced in HEK293T cell.
Species Reactivity
Mouse
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP2383
Applications
WB
Application Notes
WB (5.0-10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Ayanlaja AA, et al. 2017. Front Mol Neurosci. 10:199
2. Reiner O. 2013. Scientifica (Cairo). 2013:393975
3. Reiner O, et al. 2004. Cell Cycle. 3(6):747
2. Reiner O. 2013. Scientifica (Cairo). 2013:393975
3. Reiner O, et al. 2004. Cell Cycle. 3(6):747
Publications
Publications (0)
Neural Antibodies
Kits
For Research Use Only. Not For Clinical Use.
