Gene Therapy Tools
Creative Biolabs is a supplier of products designed for use in neuroscience research. We offer a variety of neuroscience research tools and services, covering areas such as basic research, neurological diseases, neural cell culture, and neural model construction. After extensive product development, we are pleased to announce the launch of several new tools for gene silencing and expression. Our products will assist you in achieving your research objectives, whether you are looking to knock out, knock in, knock down, or overexpress your target.
We are always expanding the product list. Please contact us and tell us your requirements and we'll customize the products according to your needs.
Product Overview
Advances in genome engineering, from the study of disease mechanisms to drug development, are enabling researchers to make unprecedented breakthroughs in neurological disorders. Our selection comprises, but is not restricted to:
- RNAi Substrates: We provide three types of small RNAs for RNAi: short hairpin RNA (shRNA), small interfering RNA (siRNA), and microRNA (miRNA). Creative Biolabs offers an extensive selection of products for many popular targets in neurological disorders, such as APOE, Tau, SOD1, CTNNB1, Huntingtin and others. We can also tailor RNAi solutions to match your specific requirements.
- Gene Expression Vectors: With our ready-to-use expression vectors, you can skip the time-consuming cloning, validation, and sequence analysis steps. We provide an array of expression systems, promoter clones, fusion tags and screening markers, and you can customize or purchase pre-made, ready-to-use expression vectors.
- Antisense Oligonucleotides (ASOs): We now have a list of ready-to-use ASO products for research into a number of neurological disorders. If you have identified a prospective RNA target and are looking for the best ASO, we can provide a customized solution.
- Viral Tracers: Viral products play a pivotal role in gene therapy, particularly as gene delivery vectors. By engineering viruses to remove their pathogenicity while preserving their delivery capabilities, viral vectors have become a cornerstone of gene therapy.
Advantages
- Strict quality control and cost-effective.
- Available on request for flexible synthesis sizes and bulk orders.
- Cover several kinds of targets for neurological disorders.
Trending Products
Alzheimer's Disease
Cat# | Product Name | Target |
NV-2106-P27 | ABCA1 Antisense Oligonucleotide (AK311445) | ABCA1 |
NEP-0421-R0053 | App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged | App |
NEP-0421-R0232 | Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged | APOE |
NEP-0421-R0140 | Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged | PSEN1 |
NV-2106-P29 | Tau Antisense Oligonucleotide (IONIS-MAPTRx) | Tau |
Parkinson's Disease
Cat# | Product Name | Target |
NEP-0521-R0864 | Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged | SNCA |
NEP-0621-R0133 | Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged | PARK7 |
NEP-0621-R0041 | Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged | PARK2 |
Amyotrophic Lateral Sclerosis
Cat# | Product Name | Target |
NEP-0521-R0748 | Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged | SOD1 |
NEP-0521-R0808 | Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged | SOD3 |
NEP-0521-R0832 | Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged | TARDBP |
NV-2106-P14 | Mouse SOD1 shRNA Silencing Adenovirus | SOD1 |
Huntington's Disease
Cat# | Product Name | Target |
NEP-0521-R0497 | Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged | HTT |
NEP-0521-R0676 | Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged | HAP1 |
Target
Expression Vectors



The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 570 bp


The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 1395 bp




Human Natural ABCA1 antisense sequence


For each gene, lentivirus vector, adenovirus vector, AAV vector are avaliblle and can be made very quickly.
- Applications:
- RNAi


Mouse Alpha-Synuclein (NM_001042451) ORF clone, mGFP Tagged
- Insert Size (bp):
- 420 bp


Human TAR DNA-Binding Protein 43 (NM_007375) ORF clone, mGFP Tagged
- Insert Size (bp):
- 1242 bp


Human Extracellular Superoxide Dismutase [Cu-Zn] (NM_003102) ORF clone, Untagged
- Insert Size (bp):
- 1500 bp


Human Superoxide Dismutase 1 (NM_000454) ORF clone, TurboGFP Tagged
- Insert Size (bp):
- 462 bp


Human Huntingtin-Associated Protein 1 (NM_177977) ORF clone, Myc-DDK Tagged
- Insert Size (bp):
- 1857 bp


Human Huntingtin (NM_002111) ORF clone, Myc-DDK Tagged
- Insert Size (bp):
- 9432 bp


Human Apolipoprotein E (APOE) (NM_000041) ORF Clone, Untagged
- Insert Size (bp):
- 954 bp


Human Presenilin 1 (PSEN1) (NM_007318) ORF Clone, TurboGFP Tagged
- Insert Size (bp):
- 1389 bp


Rat App (NM_019288) ORF Clone, Untagged
- Insert Size (bp):
- 2313 bp
















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