Gene Therapy Tools
Creative Biolabs is a supplier of products designed for use in neuroscience research. We offer a variety of neuroscience research tools and services, covering areas such as basic research, neurological diseases, neural cell culture, and neural model construction. After extensive product development, we are pleased to announce the launch of several new tools for gene silencing and expression. Our products will assist you in achieving your research objectives, whether you are looking to knock out, knock in, knock down, or overexpress your target.
We are always expanding the product list. Please contact us and tell us your requirements and we'll customize the products according to your needs.
Product Overview
Advances in genome engineering, from the study of disease mechanisms to drug development, are enabling researchers to make unprecedented breakthroughs in neurological disorders. Our selection comprises, but is not restricted to:
- RNAi Substrates: We provide three types of small RNAs for RNAi: short hairpin RNA (shRNA), small interfering RNA (siRNA), and microRNA (miRNA). Creative Biolabs offers an extensive selection of products for many popular targets in neurological disorders, such as APOE, Tau, SOD1, CTNNB1, Huntingtin and others. We can also tailor RNAi solutions to match your specific requirements.
- Gene Expression Vectors: With our ready-to-use expression vectors, you can skip the time-consuming cloning, validation, and sequence analysis steps. We provide an array of expression systems, promoter clones, fusion tags and screening markers, and you can customize or purchase pre-made, ready-to-use expression vectors.
- Antisense Oligonucleotides (ASOs): We now have a list of ready-to-use ASO products for research into a number of neurological disorders. If you have identified a prospective RNA target and are looking for the best ASO, we can provide a customized solution.
- Viral Tracers: Viral products play a pivotal role in gene therapy, particularly as gene delivery vectors. By engineering viruses to remove their pathogenicity while preserving their delivery capabilities, viral vectors have become a cornerstone of gene therapy.
Advantages
- Strict quality control and cost-effective.
- Available on request for flexible synthesis sizes and bulk orders.
- Cover several kinds of targets for neurological disorders.
Trending Products
Alzheimer's Disease
| Cat# | Product Name | Target |
| NV-2106-P27 | ABCA1 Antisense Oligonucleotide (AK311445) | ABCA1 |
| NEP-0421-R0053 | App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged | App |
| NEP-0421-R0232 | Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged | APOE |
| NEP-0421-R0140 | Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged | PSEN1 |
| NV-2106-P29 | Tau Antisense Oligonucleotide (IONIS-MAPTRx) | Tau |
Parkinson's Disease
| Cat# | Product Name | Target |
| NEP-0521-R0864 | Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged | SNCA |
| NEP-0621-R0133 | Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged | PARK7 |
| NEP-0621-R0041 | Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged | PARK2 |
Amyotrophic Lateral Sclerosis
| Cat# | Product Name | Target |
| NEP-0521-R0748 | Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged | SOD1 |
| NEP-0521-R0808 | Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged | SOD3 |
| NEP-0521-R0832 | Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged | TARDBP |
| NV-2106-P14 | Mouse SOD1 shRNA Silencing Adenovirus | SOD1 |
Huntington's Disease
| Cat# | Product Name | Target |
| NEP-0521-R0497 | Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged | HTT |
| NEP-0521-R0676 | Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged | HAP1 |
Target
Expression Vectors
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Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged [CAT#: NEP-0621-R0133]
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 570 bp
Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged [CAT#: NEP-0621-R0041]
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 1395 bp
Tau Antisense Oligonucleotide (IONIS-MAPTRx) [CAT#: NV-2106-P29]
ABCA1 Antisense Oligonucleotide (NV-2106-P27) [CAT#: NV-2106-P27]
Human Natural ABCA1 antisense sequence
Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged [CAT#: NEP-0521-R0864]
Mouse Alpha-Synuclein (NM_001042451) ORF clone, mGFP Tagged
- Insert Size (bp):
- 420 bp
Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged [CAT#: NEP-0521-R0832]
Human TAR DNA-Binding Protein 43 (NM_007375) ORF clone, mGFP Tagged
- Insert Size (bp):
- 1242 bp
Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged [CAT#: NEP-0521-R0808]
Human Extracellular Superoxide Dismutase [Cu-Zn] (NM_003102) ORF clone, Untagged
- Insert Size (bp):
- 1500 bp
Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged [CAT#: NEP-0521-R0748]
Human Superoxide Dismutase 1 (NM_000454) ORF clone, TurboGFP Tagged
- Insert Size (bp):
- 462 bp
Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged [CAT#: NEP-0521-R0676]
Human Huntingtin-Associated Protein 1 (NM_177977) ORF clone, Myc-DDK Tagged
- Insert Size (bp):
- 1857 bp
Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged [CAT#: NEP-0521-R0497]
Human Huntingtin (NM_002111) ORF clone, Myc-DDK Tagged
- Insert Size (bp):
- 9432 bp
Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged [CAT#: NEP-0421-R0232]
Human Apolipoprotein E (APOE) (NM_000041) ORF Clone, Untagged
- Insert Size (bp):
- 954 bp
Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged [CAT#: NEP-0421-R0140]
Human Presenilin 1 (PSEN1) (NM_007318) ORF Clone, TurboGFP Tagged
- Insert Size (bp):
- 1389 bp
App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged [CAT#: NEP-0421-R0053]
Rat App (NM_019288) ORF Clone, Untagged
- Insert Size (bp):
- 2313 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 528 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 528 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 528 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 528 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 528 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 525 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 525 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 525 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 525 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 528 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 528 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 528 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 528 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 525 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 525 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 528 bp
The clone can express a complete ORF with a certain tag. Different ways of expression depend on the specific nature of the gene.
- Insert Size (bp):
- 525 bp
- iNeuMab™ Anti-GD2 Antibody (NRZP-1222-ZP767) (Cat#: NRZP-1222-ZP767)
- iNeuMab™ Anti-EPHB2 Antibody (NRP-0422-P1220) (Cat#: NRP-0422-P1220)
- iNeuMab™ Anti-Integrin αvβ8 BBB Shuttle Antibody (NRZP-1222-ZP1218) (Cat#: NRZP-1222-ZP1218)
- iNeuMab™ Anti-GARP Antibody (NRP-0422-P1639) (Cat#: NRP-0422-P1639)
- iNeuMab™ Anti-CD20 Antibody (NRP-0422-P1230) (Cat#: NRP-0422-P1230)
- iNeuMab™ Anti-Alpha Synuclein Antibody (NRP-0422-P614) (Cat#: NRP-0422-P614)
- iNeuMab™ Anti-SEZ6 Antibody (NRP-0422-P517) (Cat#: NRP-0422-P517)
- iNeuMab™ Anti-FGFR1 Antibody (NRP-0422-P1244) (Cat#: NRP-0422-P1244)
- iNeuMab™ Anti-TREM2 BBB Shuttle Antibody (NRZP-1022-ZP4114) (Cat#: NRZP-1022-ZP4114)
- iNeuMab™ Anti-Tau Antibody (NRP-0422-P2275) (Cat#: NRP-0422-P2275)
- Mouse Glioma Cell Line GL261-GFP (Cat#: NCL-2108P04)
- Human Neurons Isolated from Cortex (Cat#: NCL-21P6-023)
- Mouse Midbrain Dopaminergic Neuron Cell MN9D (Cat#: NCL2110P059)
- Human Brain Microvascular Endothelial Cells (Cat#: NCL-2103-P133)
- Mouse Retinal Ganglion Cell Line RGC-5 (Cat#: NCL2110P154)
- Green Fluorescent Tau cell Line (Cat#: NCL2110P219)
- Green Fluorescent Alpha-synuclein Cell Line (Cat#: NCL2110P209)
- Human Glial (Oligodendrocytic) Hybrid Cell Line (MO3.13) (Cat#: NCL-2108P34)
- iNeu™ Human Motor Neurons (Cat#: NCL-2103-P71)
- Rat Immortalized Retinal Muller Cell Line rMC-1 (Cat#: NCL-2106-S93)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Dextran, NHS Activated (Cat#: NRZP-0722-ZP124)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- AAV2/9-hEF1a-fDIO-eNpHR 3.0-mCherry-WPRE-pA (Cat#: NTA-2012-ZP78)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein (Cat#: NRZP-0423-ZP497)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-IDS BBB Shuttle Protein (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP501)
- NeuroPro™ Anti-PON1 BBB Shuttle Protein (Cat#: NRZP-0423-ZP507)
