iNeuMab™ Anti-Rufy3 BBB Shuttle Antibody (NRZP-0423-ZP371)
[CAT#: NRZP-0423-ZP371]
- Species Reactivity:
- Rat; Mouse; Human
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-RUFY3 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 370-469 (C-terminus) of mouse Rufy3 (also known as RUN and FYVE domain-containing protein 3, Rap2-interacting protein x, Single axon-regulated protein, Singar, Singar1, KIAA0871, D5Bwg0860e and Ripx, accession number Q9D394)
Rat: 100% identity (100/100 amino acids identical)
Human: 100% identity (100/100 amino acids identical)
<50% identity with Rufy2 and other Rufy proteins
Rat: 100% identity (100/100 amino acids identical)
Human: 100% identity (100/100 amino acids identical)
<50% identity with Rufy2 and other Rufy proteins
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG2a
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
RUFY3
Official Name
RUFY3
Full Name
Rufy3
Alternative Names
KIAA0871; RIPx; Singar1; ZFYVE30
Uniprot ID
Q9D394
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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