Neural Co-Culture Cellular Model Development

Neurons perform a diversity of functions in different parts of the central nervous system (CNS) and are highly specialized for the processing and transmission of cellular signals. Other cell types, also present in the CNS, are glial cells, which have a supportive and protective function for neurons, and they also regulate neuronal function by controlling the microenvironment of neurons and play an important role in neuronal development, growth, migration, and regeneration after damage. Therefore, the establishment of neuronal and glial cell co-culture models is one of the important means to study neurological diseases in vitro and is also the basis for cellular molecular level studies of the nervous system.

Neural Co-Culture Cellular Models

Neural co-culture cellular models provided by Creative Biolabs can better simulate the in vivo environment than single cell cultures, which are closer to the in vivo traits of cells and facilitates the observation of cell-cell and cell-extracellular environment interactions, providing a better platform for in vitro experiments on molecular mechanisms of diseases and new drug development to global neuroscientists.

We can provide multiple cell co-culture modes to meet different experiments for your project.

Co-Culture Cellular Models

It can be used to study the mechanism of neuronal toxicity in ischemic stroke.

Primary cells are more compatible with in vivo studies to explain cell-cell interactions to develop new drugs for Parkinson's disease (PD).

The mixed culture of primary cells can better reflect the paracrine interaction between neurons and glial cells and can be used to study the mechanism of inflammation-related Alzheimer's disease (AD) in vitro.

At Creative Biolabs, our top research teams can provide you with multiple co-culture cell models in addition to the above.

• Co-culture of neural cell lines and non-neural cells
• Co-culture of primary brain microvascular endothelial cell lines with primary astrocytes
• Co-culture of dopamine neural cell lines
• Co-culture of primary striatal cells with primary fetal brain progenitor cells
• Co-culture of primary brain microvascular endothelial cells with cortical tissue blocks
• Co-culture of primary motor neurons with peripheral nerve cells

Custom Neural Co-Culture Cellular Models Development

For more than a decade, Creative Biolabs has been committed to cutting-edge bioscience, supplying a variety of upstream and downstream biomaterials and customized services to biologists around the world. If you need other co-culture cellular models, please contact us for details and we will customize the most suitable service for your project.