NeuroDiff™ Definitive Endoderm Kit, Animal Component-free

[CAT#: NCC200625ZP]

For the differentiation of human ES and iPS cells to definitive endoderm.

Applications:: Cell Differentiation

Cell Types:: iPSC; Embryonic Stem Cell

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Product Overview

Description

The kit is a complete, serum- and animal-free medium and supplement kit that supports the efficient differentiation of human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells into definitive endoderm cells. Cells differentiated using the kit expressed high levels of endoderm markers, including CD184 (CXCR4), SOX17, FOXA2 and c-KIT, and lacked expression of ectoderm, mesoderm and pluripotency markers. The definitive endoderm cells produced using this kit have a pluripotent effect and can be further differentiated into cells of the pancreas, intestine, lung, and liver lineage, thus providing a powerful tool for developmental research, disease modeling, and drug discovery.

Cell Types

iPSC; Embryonic Stem Cell

Species Reactivity

Human

Applications

Cell Differentiation

Research Areas

Stem Cell Research

Properties

Components

NeuroDiff™ Endoderm Basal Medium, 100 mL
NeuroDiff™ Definitive Endoderm Supplement MR (100X), 0.35 mL
NeuroDiff™ Definitive Endoderm Supplement CJ (100X), 1.1 mL