Product
NeuroMab™ Mouse Anti-Nuclear Pore Complex Proteins Monoclonal Antibody (CBP2340)
[CAT#: NAB2010327LS]
Anti-Nuclear Pore Complex Proteins Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Vertebrate; Xenopus; Yeast
- Applications:
- ICC; WB; IHC-Fr; IP
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Nuclear pores are large protein complexes that cross the nuclear envelope. The proteins that make up the nuclear pore complex are known as nucleoporins. About half of the nucleoporins typically contain solenoid protein domains-either an alpha solenoid or a beta-propeller fold, or in some cases both as separate structural domains. Each NPC contains at least 456 individual protein molecules and is composed of 30 distinct proteins (nucleoporins). The other half show structural characteristics typical of "natively unfolded" or intrinsically disordered proteins, i.e. they are highly flexible proteins that lack ordered secondary structure. These disordered proteins are the FG nucleoporins, so called because their amino-acid sequence contains many phenylalanine-glycine repeats.
Immunogen
The antibody was raised using a nuclear pore complex mixture.
Species Reactivity
Vertebrate; Xenopus; Yeast
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP2340
Applications
ICC; WB; IHC-Fr; IP
Application Notes
ICC (0.5-1 μg/mL); WB (0.2-0.5 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1727
Product Properties
Form
Liquid
Formulation
PBS, containing 0.03% Thimerosal.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
Nuclear Pore Complex Proteins
Official Name
Nuclear Pore Complex Proteins
Full Name
Nuclear Pore Complex Proteins
Alternative Names
107 kD nucleoporin; NPC proteins; Nuclear pore complex protein Nup107; Nucleoporin 107kD; Nucleoporin Nup107; NUP 107; NUP 84; NUP107; NUP153; NUP155; NUP84; NUP98
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
