iNeuMab™ Anti-CXCL12 BBB Shuttle Antibody (NRZP-1022-ZP3789)

Name: iNeuMab™ Anti-CXCL12 BBB Shuttle Antibody (NRZP-1022-ZP3789)
SKU: NRZP-1022-ZP3789
Rating: 5 (1 reviews)

[CAT#: NRZP-1022-ZP3789]

Host Species:: Mouse

Species Reactivity:: Human

Applications:: In Vitro; In Vivo; Block

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Applications

In Vitro; In Vivo; Block

Relevant Diseases

Multiple Sclerosis; Neuroinflammation

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

CXCL12

Official Name

CXCL12

Full Name

chemokine (C-X-C motif) ligand 12

Alternative Names

TPAR1; SDF1; C-X-C motif chemokine 12; Pre-B cell growth-stimulating factor; TLSF; PBSF; SDF-1; Intercrine reduced in hepatomas; IRH; hSDF-1; 3-72; SCYB12; hIRH; 3-67; Stromal cell-derived factor 1

Publications