iNeuMab™ Anti-DNMT3L BBB Shuttle Antibody (NRZP-0423-ZP94)
[CAT#: NRZP-0423-ZP94]
- Species Reactivity:
- Human
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-DNMT3L BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-387 (full-length) of human DNMT3L (also known as DNA (cytosine-5)- methyltransferase 3-like, accession number BAA95556)
Rat: 66% identity (250/377 amino acids identical)
Mouse: 65% identity (242/371 amino acids identical)
~40% identity with DNMT3A and DNMT3B
Rat: 66% identity (250/377 amino acids identical)
Mouse: 65% identity (242/371 amino acids identical)
~40% identity with DNMT3A and DNMT3B
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Research Areas
Epigenetics
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
DNMT3L
Official Name
DNMT3L
Full Name
DNMT3L
Alternative Names
DNMT3L; DNA methyltransferase 3 like
Uniprot ID
BAA95556
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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