Mouse Anti-ATXN3 Monoclonal Antibody (CBP2894)
[CAT#: NAB20101972CR]
Mouse Monoclonal (1F7E10) to ATXN3
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse
- Applications:
- WB; ELISA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
ATXN3 act as a component of the ubiquitin proteasome system, plays a role in transcriptional regulation and neuroprotection. ATXN3 interacts with RAD23, HHR23A and HHR23B, involves in the pathology of MJD. ATXN3 is a mixed-linkage, chain-editing enzyme and that the UIM region of ATXN3 regulates its substrate specificity. Contains an N-terminal deubiquitinating domain, called the Josephin domain, followed by 2 ubiquitin-interacting motifs (UIMs) and a polyQ tract near the C terminus. ATXN3 can be phosphorylated in a protein casein kinase-2-dependent manner, thus the MW would be larger than the predicted one.
Expression Host
Mammalian cells
Immunogen
ATX3,ATXN3 fusion protein Ag6627
Species Reactivity
Human; Mouse
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a
Clone Number
CBP2894
Applications
WB; ELISA
Application Notes
WB : 1:500-1:1000
Research Areas
Metabolism
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, 0.1% sodium azide and 50% glycerol pH 7.3.
Preservatives
Yes
Concentration
1000 μg/ml
Purification
Antigen affinity purification
Purity
>95%, as determined by SDS-PAGE
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -20°C. Stable for one year after shipment.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
Neural Genes
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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