Mouse Anti-Human MBP Monoclonal Antibody (CBP1592)

Product Overview

Description

The mouse anti-MBP antibody recognizes the epitope between amino acids 84 and 89 of human myelin basic protein (also known as MBP, myelin A1 protein or myelin membrane encephalopathy protein). MBP is a rich component of 304 amino acids in myelin membrane, about 33 kDa. Six potential MBP subtypes were generated by alternative splicing, four of which lacked N-terminal regions containing immunogen sequences. The mouse anti-MBP antibody is expected to recognize isoforms 1 and 2 (UniProt: P02686). The N-terminal region of MBP is highly conserved, and mouse anti-MBP antibodies are expected to have extensive cross-reactivity to maintain the isoforms of the N-terminal region. According to reports, mouse anti-MBP antibodies are suitable for Western blotting.

Immunogen

Human myelin basic protein.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP1592

Applications

IHC-Fr; IHC-P

Research Areas

Growth and Development

Conjugation

Unconjugated

Product Properties

Form

Tissue Culture Supernatant-liquid

Formulation

Tissue Culture Supernatant-liquid
0.05% Sodium Azide

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at +4°C or at -20°C if preferred.

This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.

Target

Myelin Basic Protein

Official Name

MBP

Full Name

Myelin basic protein

Alternative Names

MBP; entrez:4155; myelin basic protein; Myelin basic protein; Myelin_BP; IPR000548

Gene ID

4155(Human); 17196(Mouse); 24547(Rat)

Uniprot ID

P02686(Human); P04370(Mouse); P02688(Rat)

References

1. Martenson, R. E. (1984) Experimental allergic encephalomyelitis. A useful model of multiple sclerosis.
2. Harrower, T.P. et al. (2006) Long-term survival and integration of porcine expanded neural precursor cell grafts in a rat model of Parkinson's disease.
3. Liao, M.C. et al. (2009) Degradation of amyloid beta protein by purified myelin basic protein.

Publications