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Creative Biolabs

Mouse Anti-PPP3CA Monoclonal Antibody (CBP4325)

[CAT#: NAB2101103LS]

Anti-PPP3CA Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
WB; IHC-P

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Product Overview

Description

PPP3CA (Protein Phosphatase 3, Catalytic Subunit, Alpha Isozyme) is also known by a handful of other names, including CALNA, PPP2B, Calcineurin A Alpha, and CNA1. It is one of the subunits of the heterodimer that forms calcineurin. Calcineurin functions as a calcium-dependent, calmodulin-stimulated protein phosphatase that activates T cells via dephosphorylation of the transcription factor NFATc.

Immunogen

This monoclonal antibody was raised against a peptide sequence conjugated to KLH corresponding to amino acids 478-492 of human CnA1.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP4325

Applications

WB; IHC-P

Application Notes

WB (0.5-1 µg/mL); IHC ( 1-5 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

PPP3CA

Official Name

PPP3CA

Full Name

Protein phosphatase 3

Alternative Names

PPP3CA; Protein phosphatase 3

Gene ID

5530(Human); 19055(Mouse); 24674(Rat)

Uniprot ID

Q08209(Human); P63328(Mouse); P63329(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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