Retrovirus iPSC Reprogramming Kit, Plus

Description

Human induced pluripotent stem cells (iPSCs) may be created by reprogramming somatic cells using a specific collection of reprogramming factors, including Oct4, Sox2, Klf4, and c-Myc, which are expressed ectopically. These hiPSCs can be exploited as a renewable source for all differentiated cell types in the body since they have the same self-renewal and pluripotency characteristics as human ES cells. From patients with essentially any genetic background, human iPSCs may be produced. Retroviruses are effective vehicles for introducing heritable genes into dividing cells' genomes. Mammalian and non-mammalian cells are among the many targets of the VSV-G pseudotyped retrovirus, which is often suppressed in ES cells. Due of the retrovirus's high reprogramming effectiveness, it is frequently employed to create iPSCs. Such a chance to produce iPSCs from numerous tissues and cell types is provided by the Human iPS Cell Reprogramming Retrovirus Kit.

Cell Types

iPSC

Applications

Cell Culture

Application Notes

Highly efficiency and stable reprogramming method
Flexible in source cell selection
Optimized for feeder-free reprogramming
Addition of small molecules are not required

Shipping

Dry Ice - Overnight Shipping

Storage

Store at -80 °C. This product is stable up to 6 months when stored as directed.

Quality Control

Each lot of Human iPS Cell Reprogramming Retrovirus Kit is tested for sterility and successful reprogramming.

Research Use Only

For Research Use Only. Not for use in diagnostic or therapeutic procedures.