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Creative Biolabs

AAV Packaging Service - AAV9 Packaging

[CAT#: NRYF-0825-XY7]

We offer a comprehensive suite of services encompassing vector design, virus packaging, and analysis and testing for adeno-associated virus (AAV) applications.

Applications:
AAV9 Packaging

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Product Overview

Description

AAV9 (Adeno-associated virus serotype 9) is currently one of the most effective natural serotypes at penetrating the blood-brain barrier (BBB), allowing for widespread distribution throughout the entire brain and spinal cord after intravenous injection. Its capsid protein binds to cells via glycosylation receptors and has demonstrated long-term gene expression stability in primates.

Virus Type

Adeno-Associated Virus (AAV)

Applications

AAV9 Packaging

Application Notes

AAV9 is already approved for clinical treatment of Spinal Muscular Atrophy (SMA). In basic research, AAV9 is commonly used to deliver the CRISPR-Cas9 system to the entire brain for constructing neurodegenerative disease models. Furthermore, its ability to target heart muscle also makes it useful in cardiovascular disease research.
Properites

Shipping

Dry ice

Storage

-80°C

Quality Control

AAV purity is above 95% and endotoxin is less than 10 EU/mL, which is suitable for cell and animal experiments that are sensitive to virus purity.

Research Use Only

For Research Use Only. Not for Use in Therapeutic or Diagnostic Procedures.
Creative Biolabs is a contract manufacturer that produces tailored viruses and vectors according to client specifications. Importantly, this manufacturing service does not grant Creative Biolabs any intellectual property ownership; all designs and associated intellectual property rights remain exclusively with the customer.
Certain vector components may be subject to third-party intellectual property rights. Creative Biolabs offers publicly available sequence information for these components as a convenience for reference only. The customer assumes full responsibility and liability for the use of these components in their custom vectors. By purchasing vectors containing such components, the customer confirms they have secured all necessary intellectual property licenses, including the right to engage Creative Biolabs for manufacturing.
Publications

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For Research Use Only. Not For Clinical Use.
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