Astrocyte-to-Neuron Conversion Reprogramming Service

Astrocytes offer more than just structural support to neurons. Research has unveiled that astrocytes play a critical role in brain function and have the potential to transform into neurons under specific conditions. This fascinating process, known as astrocyte-to-neuron conversion, involves reprogramming astrocytes into neurons using various genetic and chemical factors. With the potential to revolutionize the field of neuroscience, Creative Biolabs proudly presents our Astrocyte-to-Neuron Conversion Reprogramming Service, a cutting-edge technology that aims to convert astrocytes into fully-functional neurons.

Our Capabilities

Our Astrocyte-to-Neuron Conversion Reprogramming Service utilizes a combination of genetic and chemical factors to induce astrocytes to differentiate into fully-functional neurons. This service has several advantages over other reprogramming techniques, including:

• Efficiency: Our service has a high efficiency rate, meaning that a large percentage of astrocytes can be successfully converted into neurons.
• Specificity: Our service is highly specific, meaning that only astrocytes are targeted for conversion, leaving other cell types untouched.
• Safety: Our service utilizes non-integrating vectors, which minimizes the risk of genetic mutations and other safety concerns.

Fig.1 Astrocytes direct reprogramming. (Chouchane, 2012)

QC Characterization of Neurons

Our neuronal characterization services provide detailed analysis of the physiological and morphological properties of neurons, including but not limited to the following:

Applications

Our Astrocyte-to-Neuron Conversion Reprogramming Service has numerous applications in the field of neuroscience, including:

• Disease modeling: Our service can be used to create patient-specific neurons for disease modeling, which can help identify potential therapeutic targets and drug candidates.
• Drug discovery: Our service can be used to test the efficacy of potential drug candidates on patient-specific neurons, which can help identify promising treatments for neurological disorders.
• Cell therapy: Our service can be used to create fully-functional neurons for use in cell therapy, which can help treat a wide range of neurological disorders.

Creative Biolabs' scientists have extensive experience in the field of neuroscience and are dedicated to providing high-quality services to their clients. We always work closely with clients to develop customized protocols that meet their specific needs and ensure that the results of their experiments are reliable and reproducible. Get in touch with us today to find out more about how we can support you in your endeavors!

Reference

1. Chouchane, Melek, and Marcos R. Costa. "Cell therapy for stroke: use of local astrocytes." Frontiers in cellular neuroscience 6 (2012): 49.