iNeuMab™ Anti-Gephyrin BBB Shuttle Antibody (NRZP-0423-ZP134)
[CAT#: NRZP-0423-ZP134]
- Species Reactivity:
- Human; Mouse; Rat
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-Gephyrin BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-181 (N-terminus) of human Gephyrin (also known as Molybdopterin molybdenumtransferase, MPT Mo-transferase, Domain G, Domain E, Putative glycine receptor-tubulin linker protein, GPHN, GPH and KIAA1385, accession number Q9NQX3) Mouse: 100% identity (181/181 amino acids identical)
Rat: 100% identity (181/181 amino acids identical) with isoform 5, slightly lower with other isoforms
Rat: 100% identity (181/181 amino acids identical) with isoform 5, slightly lower with other isoforms
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Isotype
IgG2a
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
Gephyrin
Official Name
GPHN
Full Name
Gephyrin
Alternative Names
GPHN; GEPH; GPH; GPHRYN; HKPX1; MOCODC; gephyrin
Uniprot ID
Q9NQX3
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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