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Creative Biolabs

LC3A and LC3B Antibody Duo

[CAT#: NRZP-0323-ZP128]

Microtubule-associated protein 1 light chain 3 alpha (LC3A) and Microtubule-associated protein 1 light chain 3 beta (LC3B) Antibody Duo

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Description

Autophagy is a regulated mechanism that disassembles unnecessary or dysfunctional cellular components. Targeted constituents are enclosed by autophagosomes, double-membraned vesicles. LC3s, including MAP1-LC3A, B, and C, are autophagosomal membrane proteins and biomarkers of autophagy. They bind to PE to form autophagosomes that fuse with lysosomes to break down enclosed components. LC3A and B staining minimally co-localize in the cytoplasm, indicating that only one LC3 protein is involved in relevant autophagosome formation.
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Components

anti-LC3A antibody
anti-LC3B antibody
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For Research Use Only. Not For Clinical Use.
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