NeuroMab™ Anti-Presenilin 1 BBB Shuttle Antibody(NRZP-1022-ZP3396)
[CAT#: NRZP-1022-ZP3396]
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; Inhib; Block; In Vitro
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Host Species
Mouse
Applications
WB; Inhib; Block; In Vitro
Relevant Diseases
Alzheimer's Disease
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
Presenilin1
Official Name
PSEN1
Full Name
Presenilin-1
Alternative Names
PSEN1
Product Pictures
Viability
Figure 1 Viability analysis of the tumor cell line MCF7 in the presence of anti-presenilin 1 antibody.
Viability
figure 2. Viability analysis of tumor cell line PC3 in the presence of anti-presenilin 1 antibody.
Viability
Figure 3. Viability analysis of the tumor cell line CAL33 in the presence of anti-presenilin 1 antibody.
Viability
Figure 4. Viability analysis of the tumor cell line HCT116 in the presence of anti-presenilin 1 antibody.
Viability
Figure 5. Viability analysis of the tumor cell line MEF in the presence of anti-presenilin 1 antibody.
WB
Figure 6. Western blot Figures of NOTCH, NFKb and IKKb proteins in MCF7 cells treated with anti-presenilin 1 antibody
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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