NeuroMab™ Anti-Nav1.2 sodium channel, Clone K69/3 (CBP8380)

Product Overview

Immunogen

Fusion protein amino acids 1882-2005 (cytoplasmic C-terminus, RFMASNPSKVSYEPI TTTLKRKQEEVSAIVIQRAYRRYLLKQKVKKVSSIYKKDKGKEDEGTPIKEDIITD KLNENSTPEKTDVTPSTTSPPSYDSVTKPEKEKFEKDKSEKEDKGKDIRESKK) of rat Voltage-gated sodium channel subunit alpha Nav1.2, Sodium channel protein type 2 subunit alpha, Sodium channel protein brain II subunit alpha, HBSC II, NAC2, Scn2a, Scn2a1, Scn2a2, accession number P04775)
Mouse: 100% identity (124/124 amino acids identical)
Human: 94% identity (117/124 amino acids identical)
>60% identity with Nav1.1, Nav1.3 and Nav1.7

Species Reactivity

Rat; Mouse; Human

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

CBP8380

Applications

WB; IHC; IP; ICC

Application Notes

Does not cross-react with Nav1.1/3/7

Research Areas

Na+ channels

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

SCN2A

Official Name

SCN2A

Full Name

Nav1.2 Na+ channel

Alternative Names

Sodium Voltage-Gated Channel Alpha Subunit 2; Sodium Channel; Voltage-Gated; Type II; Alpha 2 Polypeptide; Sodium Channel; Voltage-Gated; Type II; Alpha 1 Polypeptide; Sodium Channel; Voltage-Gated; Type II; Alpha Subunit; Voltage-Gated Sodium Channel Subunit Alpha Nav1.2; Sodium Channel Protein Brain II Subunit Alpha; Sodium Channel Protein Type II Subunit Alpha; HBSC II; SCN2A1; SCN2A2; NAC2; Sodium Channel; Voltage Gated; Type II Alpha Subunit; Sodium Channel Protein; Brain Type 2 Alpha Subunit;

Uniprot ID

P04775

Product Pictures

Fig. 1 Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with K69/3 (left) or N52A/42 (right) TC supe.